When the Dor Yeshorim organization was set up in New York and Israel in 1983, Tay-Sachs disease was rife in the Jewish community. Rabbi Joseph Ekstein, its founder, lost four children to the condition. The mutated gene that causes the disorder, which usually kills children before the age of 8, is ten times more common among Ashkenazi Jews (of European descent) than in most other ethnic groups. Jewish marriage customs made it highly likely that two carriers would start a family together, with a one in four risk that every child would be affected.
How a Community Stamped out Tay-Sachs with Screening
When the Dor Yeshorim organization was set up in New York and Israel in 1983, Tay-Sachs disease was rife in the Jewish community. Rabbi Joseph Ekstein, its founder, lost four children to the condition. The mutated gene that causes the disorder, which usually kills children before the age of 8, is ten times more common among Ashkenazi Jews (of European descent) than in most other ethnic groups. Jewish marriage customs made it highly likely that two carriers would start a family together, with a one in four risk that every child would be affected.
